If your desktop icons disappear the first thing you should try is right clicking on the desktop, then choose Arrange icons by.. -> make sure Show icons is checked!

If your taskbar is gone move your mouse over the place where it usually is, if it appears right click on it and make sure that Auto-hide is turned off. Try moving your mouse cursor all over your desktop since you might have dragged the taskbar to a new position (on top, to the right, to the left…).

If your desktop icons and the taksbar are gone then press Ctrl+Alt+Del on your keyboard to bring up the Task Manager. Open the Processes tab and find explorer.exe, click on it then click the End process button. After that click File -> New task (Run)… -> Type explorer.exe and click OK.

If that doesn’t fix the problem then a full virus and malware scan is in order, turn off System Restore, reboot your computer in Safe Mode, ran a complete scan with Malwarebytes’ Anti-Malware then reboot normally and turn System Restore back on. Run a scan with your Antivirus program following the same steps.

More things to try:

Press Ctrl+Alt+Del on your keyboard to bring up the Task Manager, click File -> New task (Run)… -> Type msconfig and click OK. Open the startup tab, if you see ipmon32 uncheck it, reboot.

Try using System Restore to restore your computer back to a previous working state.

Do you have thumb drive plugged in? Remove it and see if that helps.

Good luck!